CHICAGO (Reuters) - Bariatric Surgery appears to alter the metabolism of the body of a regime so weight loss alone may help explain why diabetes often disappears after surgery before even that much weight is lost, U.S. researchers said on Wednesday.
Understand how gastric bypass affects metabolism could shed light on the treatment of type 2 diabetes, exercise a global epidemic strongly linked to obesity and too little.
Bariatric Surgery becomes more and more popular as obese people struggle to lose weight and avoid health complications that accompany the additional books - including diabetes, heart disease, joint pain, and certain cancers.
In research conducted at Columbia University in New York and the Duke University in North Carolina, researchers studied two small groups of severely obese patients with diabetes who had gastric bypass surgery or went on a strict diet.
Both groups have lost about 20 pounds.
The study, the chemical metabolites - sous-products measured teams of foods in the body.
They found that unlike plans changes bypass gastric metabolism of a person by significantly from reduction of amino acids levels - compounds in circulation linked with resistance to insulin, diabetes and obesity.
"What we were trying to do, it is cast a wide net," said Christopher Newgard of the Duke, who worked on the study published in Science Translational Medicine."
"What we have is a very clear difference between surgery Bariatric and dietary intervention."
He said patients in the Group of surgery of the lower levels of acid molecules called amino branch of the chain.
"These dropped much more rapidly in people with Bariatric Surgery than people with dietary intervention", he said.
People in the gastric bypass in the study arm underwent surgery called Roux-en-Y, where doctors surgically reduces the size of the stomach to stop people from eating too much.
Newgard said that it was not clear why reduce the size of the stomach could have this effect, but it is clear that bariatric surgery causes significant metabolic changes.
The team is now research to discover ways to develop drugs could reproduce this effect.
Newgard said that the results could apply not device weight loss of Lap-Band of Allergan, in which doctors insert a strip of adjustable silicone around the upper part of the stomach, but do not reduce the size of the stomach surgically.
Up to one third of the adult U.S. could suffer from diabetes in 2050, according to the Centers for Disease Control and Prevention.
(Edited by Cynthia Osterman)
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