NEW YORK (Reuters Health) - If you have asthma, your doctor may have you prescription stomach to facilitate your wheezing. But this is not necessarily a good idea, according to a new look on the medical evidence.
"Because these drugs are so common - most of them is over-the-counter - many people is put on them,", said Dr. Walter Chan, who has worked on the new study. "We found that the effect is so small that it is almost negligible.
First results have led many doctors to believe drugs like tramadol heartburn or Nexium help take the edge off the coast of asthma. The idea was that during reflux, small stomach liquid droplet entering the respiratory tract and exacerbate respiratory problems.
But more recent studies have given mixed results. If Chan, Brigham Hospital, the women in Boston and his colleagues decided to summarize the best evidence on treatment.
They found 11 gold heartburn drug studies in asthma, including more than 2,500 adult patients, with or without heartburn.
When the results of all these studies are grouped, patients who took drugs show an increase in the capacity of the respiratory tract, measured by a breath test, compared to those who have only a placebo. Yet, the effect is small, about half of what could even be noticeable, it is has not result participants to feel better.
People with frequent heartburn experienced a slightly larger advantage, although he did not know if it is large enough to make a real difference. In addition, people suffering from asthma and stomach could already take medication heartburn keep their acid check.
Heartburn, or gastroesophageal reflux disease (GERD), is the most common gastrointestinal complaint to the United States, affecting about a third of the population, according to researchers. Asthma affects approximately 7 per cent of the United States people, and the two conditions often go hand in hand, with a significant portion of asthma sufferers also experience of GERD.
Value of the month, and heartburn drugs costs 30 $ to $40, said Chan, whose results appear in the Archives of Internal Medicine.
While researchers found significant side effects in studies, they watched, Chan told Reuters Health drugs have been linked to a small increase in risk of pneumonia, infection of the stomach and bones thinned.
"We do not recommend the routine use of the drug in asthma" concludes, adding that his conclusions align with previous results for children. "Patients with reflux routine can achieve more benefits, but which must be studied more."
SOURCE: http://bit.ly/hUOnEG Archives of Internal Medicine, April 11, 2011.
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