2011年4月20日星期三

Diet of pregnant women linked to childhood obesity: study (AFP)

WELLINGTON (AFP) - a future mother during pregnancy diet can alter the DNA of her baby in the uterus increasing the risk of obesity, cardiovascular disease and diabetes life, an international study has found.

Researchers, said that the study provides the first scientific evidence linking the diet of pregnant women in childhood obesity, with major implications for public health.

"This a breakthrough major because for the first time he gives us the opportunity to work with the optimal diet, a mother should eat,"Professor Peter Gluckman, Liggins Institute University of Auckland told AFP."."

"It is likely to vary slightly from mother to mother, but it might be a major tool in the fight against the obesity epidemic."

The study, conducted by scientists in Britain, New Zealand and Singapore, has shown that a mother ate while pregnant could change the function of the DNA of his child by a process called epigenetic changes.

Children with a high degree of epigenetic changes were more likely to develop a metabolism which "establishes more fatty" and become obese, researchers found.

These children were about three kilograms (6.6 pounds) more heavy that their peers at the time where they were between the ages of six to nine, said Gluckman.

"It's a hell of lot of extra weight at this age, he said, adding that extra fat was likely to be transported to the adult age, increase the chances of developing diabetes and heart disease."

The researchers used fabric cord for measuring the rate of epigenetic change in 300 infants, then discussed if it was linked to the weight of the children when they were between the ages of six to nine.

"The correlation was very strong, that we thought first of all, so that we the replicated again and again", said Gluckman.

The study revealed the effect was not bound either the mother or the baby's weight at birth, which means that a thin woman could offer a little baby who still added became obese because of changes triggered by the diet in the uterus.

Gluckman, said the pace of epigenetic changes was perhaps related to a low-carbohydrate diet, in the first three months of pregnancy but it was too early to reach a final conclusion, and further studies are needed.

He said a theory is that embryo fed with a diet containing low - carbohydrates that provide the body with energy, assumed it would be born into a poor in carbohydrates and amended accordingly its metabolism environment.

This meant that it stored more fat, which could be used as fuel when food was scarce.

Gluckman, said the study, which will be published next week in the journal of diabetes, confirmed the suspicions long poor prenatal nutrition could have a major impact on heath adult.

This meant responsible for health, fight against obesity soaring, rates should consider policies to improve the health of pregnant women, instead of simply focusing on trying to help obese adults, he said.

"It provides the most convincing argument yet to give more weight to the improvement of maternal and child health as a means to reduce the burden of chronic disease".


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