2011年5月21日星期六

Study sees the link between Psoriasis, obesity in children (HealthDay)

(Friday, 20 may HealthDay News) - the prevalence of psoriasis - a chronic inflammatory disease of the skin - is significantly higher in overweight children and obésités, researchers found.

The study of Kaiser Permanente, published online in the journal of Pediatrics, also found that adolescents with psoriasis (regardless of their body weight) have higher cholesterol, putting them at greater risk for heart disease.

"This study suggests a link between obesity and psoriasis in children," lead author of the study Corinna Koebnick, researcher, Department of research & evaluation of the Kaiser Permanente Southern California, said in a press release of Kaiser Permanente.

"But our findings also suggest that the increased risk of heart disease in patients with psoriasis begins in childhood in the form of higher levels of cholesterol." "We might need to monitor the young patients of psoriasis more closely to cardiovascular risk factors, especially if they are obese,", Koebnick said.

With the aid of electronic health records to study 710,949 children various racial and ethnic, researchers have discovered the obese children were almost 40 per cent more likely to have psoriasis that children of normal weight. Even more at risk, extremely obese children were almost 80 per cent more likely to have psoriasis that children of normal weight. In addition, it was four times more likely to psoriasis to be severe or more widespread among the young obese and normal weight children.

The study also revealed that, compared to children without psoriasis, teen with the State of the skin had 4 to 16 per cent of the higher levels of cholesterol and liver enzymes, regardless of their weight.

Psoriasis, often seen simply as a condition of the heaviness of the skin, may put children at risk of metabolic disease (like diabetes, metabolic syndrome and heart disease), as in adults, the study authors noted.

"It has been well described that adults with psoriasis have increased cardiovascular risk factors, but now, we examined these issues in children," the study's main author, Dr. Jashin j. Wu, Director of clinical research and residency program associate and Director of the Department of Dermatology at the Medical Centre of Kaiser Permanente Los Angeles, said in the press release.

"As follow us these patients over 30 to 40 years, we will be able to determine if these increased cardiovascular risk factors increase in turn the risk for major adverse cardiac events," said Wu.

The researchers acknowledged that the study had limitations due to its transversal design, where body weight and information on psoriasis were assessed at the same time and stated that these issues would be met in future studies.

More information

The American Academy of Pediatrics provides details on childhood obesity.


View the original article here

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